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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 669558Generated: October 29, 2026

2-Fluoro-5-(trifluoromethyl)phenyl isocyanate → 1-(2-Fluoro-5-(trifluoromethyl)phenyl)-3-(2-fluoro-4-(3-oxo-3,4-dihydro pyrido[2,3-b]pyrazin-8-yloxy)phenyl)urea

https://huagongshe.com/reaction/669558

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-5-(trifluoromethyl)phenyl isocyanateHCID 2733380—
Reactant8-(4-amino-3-fluorophenoxy)pyrido[2,3-b]pyrazin-3(4H)-oneHCID 46900932—
Product1-(2-Fluoro-5-(trifluoromethyl)phenyl)-3-(2-fluoro-4-(3-oxo-3,4-dihydro pyrido[2,3-b]pyrazin-8-yloxy)phenyl)ureaHCID 44133914—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-44ed9307f574477c90aca319360fca82
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)