Water → Methyl 3-bromo-5-(5-chloropyridin-2-yl)benzoate

HRID 669596Notes

Reaction equation

HRID 669596 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[O:7][CH3:8])[cH:9][c:10]([B:12]2[O:13][C:14]([CH3:15])([CH3:16])[C:17]([CH3:18])([CH3:19])[O:20]2)[cH:11]1.[Br:21][c:22]1[n:23][cH:24][c:25]([Cl:28])[cH:26][cH:27]1.[CH:29]([NH:30][CH:31]([CH3:32])[CH3:33])([CH3:34])[CH3:35].[O:36]=[CH:37][N:38]([CH3:39])[CH3:40].[OH2:41]>>[Br:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[O:7][CH3:8])[cH:9][c:10](-[c:22]2[n:23][cH:24][c:25]([Cl:28])[cH:26][cH:27]2)[cH:11]1

Participants

6

Reactant 5

HCID 962WaterHCID 6228DimethylformamideHCID 7912DiisopropylamineHCID 8170982-Bromo-5-chloropyridineHCID 53436914Methyl 3-bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)benzoate

Product 1

HCID 66649929Methyl 3-bromo-5-(5-chloropyridin-2-yl)benzoate

Sources & evidence

ORD record
ord-a67772bc698a4a8fb71471eea7e1cb5d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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