Dichloromethane → HCID 57750272, compound

HRID 669612Notes

Reaction equation

[Cl:48][CH2:49][Cl:50].[Cl:8][c:9]1[cH:10][cH:11][c:12]([CH:15]([CH2:16][n:17]2[n:18][cH:19][cH:20][cH:21]2)[NH:22][C:23](=[O:24])[C:25]2([NH:40][C:41](=[O:42])[O:43][C:44]([CH3:45])([CH3:46])[CH3:47])[CH2:26][CH2:27][N:28]([c:31]3[c:32]4[c:33]([n:34][cH:35][n:36]3)[nH:37][cH:38][cH:39]4)[CH2:29][CH2:30]2)[cH:13][cH:14]1.[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7]>>[Cl:8][c:9]1[cH:10][cH:11][c:12]([CH:15]([CH2:16][n:17]2[n:18][cH:19][cH:20][cH:21]2)[NH:22][C:23](=[O:24])[C:25]2([NH2:40])[CH2:26][CH2:27][N:28]([c:31]3[c:32]4[c:33]([n:34][cH:35][n:36]3)[nH:37][cH:38][cH:39]4)[CH2:29][CH2:30]2)[cH:13][cH:14]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 57750325tert-butyl 4-(1-(4-chlorophenyl)-2-(1H-pyrazol-1-yl)ethylcarbamoyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-ylcarbamate

Product 1

HCID 57750272HCID 57750272, compound

Sources & evidence

ORD record: ord-93023b1d96c449758f98f89c2e1795a0
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…