p-Toluenesulfonic acid monohydrate → Butanoic acid, 4-(2-oxocyclopentyl)-, ethyl ester

HRID 66964Notes

Reaction equation

HRID 66964 reaction equation
[C:1]([CH2:4][CH2:5][CH2:6][CH:7]1[CH2:11][CH2:10][CH2:9][C:8]1=[O:12])([OH:3])=[O:2].O.[C:14]1(C)C=CC(S(O)(=O)=O)=C[CH:15]=1>C(O)C>[C:1]([CH2:4][CH2:5][CH2:6][CH:7]1[CH2:11][CH2:10][CH2:9][C:8]1=[O:12])([O:3][CH2:14][CH3:15])=[O:2]

Participants

4

Reactant 2

HCID 521998p-Toluenesulfonic acid monohydrateHCID 558495Butanoic acid, 4-(2-oxocyclopentyl)-

Product 1

HCID 558493Butanoic acid, 4-(2-oxocyclopentyl)-, ethyl ester

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In the manner described in Example 3, treatment of 2-(3-carboxypropyl)cyclopentan-1-one (Example 5) with p-toluenesulfonic acid monohydrate in ethanol gives a colorless oil, b.p. 93° C. (0.10 mm).

Workup

  1. customgives a colorless oil, b.p. 93° C. (0.10 mm)

Sources & evidence

ORD record
ord-90d5b44bfab549d6849a1880c146d9b3
Source dataset
uspto-grants-1982_08
Patent number
US04343949

Reaction notes

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