Carbon Tetrachloride → 7-Chloro-2-(4-fluorophenyl)-3-[2-(1-pyrrolidinyl)-4-pyrimidinyl]-6-(trifluoromethyl)pyrazolo[1,5-a]pyridine
Reaction equation
[C:37]([Cl:38])([Cl:39])([Cl:40])[Cl:41].[CH2:32]([Li:33])[CH2:34][CH2:35][CH3:36].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][n:10]3[c:11]([cH:12][cH:13][c:14]([C:16]([F:17])([F:18])[F:19])[cH:15]3)[c:20]2-[c:21]2[n:22][c:23]([N:27]3[CH2:28][CH2:29][CH2:30][CH2:31]3)[n:24][cH:25][cH:26]2)[cH:6][cH:7]1.[O:42]1[CH2:43][CH2:44][CH2:45][CH2:46]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][n:10]3[c:11]([cH:12][cH:13][c:14]([C:16]([F:17])([F:18])[F:19])[c:15]3[Cl:38])[c:20]2-[c:21]2[n:22][c:23]([N:27]3[CH2:28][CH2:29][CH2:30][CH2:31]3)[n:24][cH:25][cH:26]2)[cH:6][cH:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-4a8bd2008dbe46019c6e1931e260aaaf
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…