Dichloromethane → 4-(4-bromo-2-fluorophenoxy)-6-methoxy-7-(3-(N-methylsulphonylamino)propoxy)quinazoline
Reaction equation
[CH3:27][CH2:28][N:29]([CH2:30][CH3:31])[CH2:32][CH3:33].[CH3:34][S:35]([Cl:36])(=[O:37])=[O:38].[Cl:39][CH2:40][Cl:41].[NH2:1][CH2:2][CH2:3][CH2:4][O:5][c:6]1[c:7]([O:25][CH3:26])[cH:8][c:9]2[c:10]([O:16][c:17]3[c:18]([F:24])[cH:19][c:20]([Br:23])[cH:21][cH:22]3)[n:11][cH:12][n:13][c:14]2[cH:15]1>>[NH:1]([CH2:2][CH2:3][CH2:4][O:5][c:6]1[c:7]([O:25][CH3:26])[cH:8][c:9]2[c:10]([O:16][c:17]3[c:18]([F:24])[cH:19][c:20]([Br:23])[cH:21][cH:22]3)[n:11][cH:12][n:13][c:14]2[cH:15]1)[S:35]([CH3:34])(=[O:37])=[O:38]Participants
5
Sources & evidence
- ORD record
- ord-5e3ba52699ad4625921b60cccaf204b7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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