Dichloromethane → 1h-Indole-1-carboxylic acid,5-(benzoylamino)-2,3-dihydro-,1,1-dimethylethyl ester

HRID 670548Notes

Reaction equation

HRID 670548 reaction equation
[C:10]([CH3:11])([CH3:12])([CH3:13])[O:14][C:15](=[O:16])[N:17]1[CH2:18][CH2:19][c:20]2[cH:21][c:22]([NH2:26])[cH:23][cH:24][c:25]21.[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)(=[O:8])[Cl:9].[CH3:27][CH2:28][N:29]([CH2:30][CH3:31])[CH2:32][CH3:33].[Cl:34][CH2:35][Cl:36]>>[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)(=[O:8])[NH:26][c:22]1[cH:21][c:20]2[c:25]([cH:24][cH:23]1)[N:17]([C:15]([O:14][C:10]([CH3:11])([CH3:12])[CH3:13])=[O:16])[CH2:18][CH2:19]2

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 7412Benzoyl chlorideHCID 8471TriethylamineHCID 22240520tert-Butyl 5-amino-2,3-dihydro-1H-indole-1-carboxylate

Product 1

HCID 668890921h-Indole-1-carboxylic acid,5-(benzoylamino)-2,3-dihydro-,1,1-dimethylethyl ester

Sources & evidence

ORD record
ord-c6d69c9ca1aa40eaa6e830887e8a6d70
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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