Dichloromethane → N-(5-bromo-2-pyridinyl)-3-cyclohexyl-2-[4-methylsulfonyl-3-(trifluoromethyl)phenyl]prop-2-enamide
Reaction equation
[Br:20][N:21]1[C:22](=[O:23])[CH2:24][CH2:25][C:26]1=[O:27].[CH2:61]([Cl:62])[Cl:63].[CH:28]1([CH:34]=[C:35]([C:36](=[O:37])[OH:38])[c:39]2[cH:40][c:41]([C:49]([F:50])([F:51])[F:52])[c:42]([S:45](=[O:46])(=[O:47])[CH3:48])[cH:43][cH:44]2)[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]1.[NH2:53][c:54]1[n:55][cH:56][c:57]([Br:60])[cH:58][cH:59]1.[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[CH:28]1([CH:34]=[C:35]([C:36](=[O:38])[NH:53][c:54]2[n:55][cH:56][c:57]([Br:60])[cH:58][cH:59]2)[c:39]2[cH:40][c:41]([C:49]([F:50])([F:51])[F:52])[c:42]([S:45](=[O:46])(=[O:47])[CH3:48])[cH:43][cH:44]2)[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-65a75df0d9c24425a91790a98962ced1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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