反应详情

A mixture of 0.5 gm of 2-(chloroacetyl-amino)-6-amino-benzo[1,2-d:5,4-d']bisthiazole, 0.7 gm of diethylamine and 3 ml of dioxane was refluxed for 2 hours. Then, the solvent was evaporated in vacuo, the residue was dissolved in ethyl acetate, and the solution was washed with water and dried over sodium sulfate. After evaporation of the solvent, 0.3 gm (60% of theory) of the title compound, M.P. 203°-205° C. (from ethanol/dimethylformamide) were obtained.

1. temperaturewas refluxed for 2 hours
2. customThen, the solvent was evaporated in vacuo
3. dissolutionthe residue was dissolved in ethyl acetate
4. washthe solution was washed with water
5. dry with materialdried over sodium sulfate
6. customAfter evaporation of the solvent, 0.3 gm (60% of theory) of the title compound
7. customM.P. 203°-205° C. (from ethanol/dimethylformamide) were obtained