反应详情

500 mgm of chloroacetyl chloride were added to a stirred solution of 950 gm of 2-(diethylamino-acetylamino)6-amino-benzo[1,2-d:5,4-d']bisthiazole in 5 ml of dimethylformamide at 0° to 5° C. The mixture was heated for 30 minutes on a waterbath, then cooled, admixed with 50 ml of water and made alkaline with pyridine. The resulting precipitate was collected, washed and recrystallized from dimethylformamide.

1. temperatureThe mixture was heated for 30 minutes on a waterbath
2. temperaturecooled
3. customThe resulting precipitate was collected
4. washwashed
5. customrecrystallized from dimethylformamide