Acetic Acid → 4-{[(2,4-Dichloro-thiazol-5-yl)methyl]-isobutyl-amino}-piperidine-1-carboxylic acid t-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([NH:14][CH2:15][c:16]2[c:17]([Cl:22])[n:18][c:19]([Cl:21])[s:20]2)[CH2:12][CH2:13]1.[C:32]([O:33][BH-:34]([O:35][C:36](=[O:37])[CH3:38])[O:39][C:40](=[O:41])[CH3:42])(=[O:43])[CH3:44].[C:55]([O:56][CH3:57])([CH3:58])([CH3:59])[CH3:60].[CH3:23][C:24](=[O:25])[OH:26].[CH:27]([CH:28]([CH3:29])[CH3:30])=[O:31].[Cl:46][c:47]1[s:48][c:49]([CH2:50][OH:51])[c:52]([Cl:53])[n:54]1.[Na+:45]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([N:14]([CH2:15][c:16]2[c:17]([Cl:22])[n:18][c:19]([Cl:21])[s:20]2)[CH2:27][CH:28]([CH3:29])[CH3:30])[CH2:12][CH2:13]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-410e1252bc9d448bbc58a08620d8e870
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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