Water → 2-methylpropyl 3-[5-[1-(4H-1,3-benzodioxin-7-yl)-2-(2,2-difluoropropanoylamino)propoxy]indazol-1-yl]benzoate
Reaction equation
[CH2:69]([N:70]([CH:71]([CH3:72])[CH3:73])[CH:74]([CH3:75])[CH3:76])[CH3:77].[Cl:78][CH2:79][Cl:80].[F:38][C:39]([C:40](=[O:41])[OH:42])([CH3:43])[F:44].[NH2:1][CH:2]([CH:3]([O:4][c:5]1[cH:6][c:7]2[cH:8][n:9][n:10](-[c:14]3[cH:15][c:16]([C:17](=[O:18])[O:19][CH2:20][CH:21]([CH3:22])[CH3:23])[cH:24][cH:25][cH:26]3)[c:11]2[cH:12][cH:13]1)[c:27]1[cH:28][cH:29][c:30]2[c:31]([cH:36]1)[O:32][CH2:33][O:34][CH2:35]2)[CH3:37].[OH2:81].[P-:45]([F:46])([F:47])([F:48])([F:49])([F:50])[F:51].[n:52]1([O:53][C:54]([N:55]([CH3:56])[CH3:57])=[N+:58]([CH3:59])[CH3:60])[c:61]2[cH:62][cH:63][cH:64][cH:65][c:66]2[n:67][n:68]1>>[NH:1]([CH:2]([CH:3]([O:4][c:5]1[cH:6][c:7]2[cH:8][n:9][n:10](-[c:14]3[cH:15][c:16]([C:17](=[O:18])[O:19][CH2:20][CH:21]([CH3:22])[CH3:23])[cH:24][cH:25][cH:26]3)[c:11]2[cH:12][cH:13]1)[c:27]1[cH:28][cH:29][c:30]2[c:31]([cH:36]1)[O:32][CH2:33][O:34][CH2:35]2)[CH3:37])[C:40]([C:39]([F:38])([CH3:43])[F:44])=[O:41]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-b15839d381e34db78402506fa29c7ddd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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