Dimethylformamide → 2-[2-Amino-4-(1,3-dihydroisoindole-2-carbonyl)quinazolin-6-yl]benzenesulfonyl chloride
Reaction equation
[NH2:5][c:6]1[n:7][c:8]2[cH:9][cH:10][c:11](-[c:27]3[c:28]([S:33](=[O:34])(=[O:35])[OH:36])[cH:29][cH:30][cH:31][cH:32]3)[cH:12][c:13]2[c:14]([C:16](=[O:17])[N:18]2[CH2:19][c:20]3[cH:21][cH:22][cH:23][cH:24][c:25]3[CH2:26]2)[n:15]1.[O:37]=[CH:38][N:39]([CH3:40])[CH3:41].[S:1]([Cl:2])([Cl:3])=[O:4]>>[Cl:3][S:33]([c:28]1[c:27](-[c:11]2[cH:10][cH:9][c:8]3[n:7][c:6]([NH2:5])[n:15][c:14]([C:16](=[O:17])[N:18]4[CH2:19][c:20]5[cH:21][cH:22][cH:23][cH:24][c:25]5[CH2:26]4)[c:13]3[cH:12]2)[cH:32][cH:31][cH:30][cH:29]1)(=[O:34])=[O:36]Participants
4
Sources & evidence
- ORD record
- ord-02c08c27b0f140d29143ccc2ee05fc76
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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