Potassium Cation → Tert-butyl 3-(4-bromo-2-methylphenyl)pyrrolidine-1-carboxylate

HRID 671520Notes

Reaction equation

HRID 671520 reaction equation
[Br:11][c:12]1[cH:13][c:14]([CH3:35])[c:15]([CH:18]([CH2:19][CH2:20][O:21][S:22]([CH3:23])(=[O:24])=[O:25])[CH2:26][NH:27][C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[cH:16][cH:17]1.[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[CH3:2][Si:3]([N-:4][Si:5]([CH3:6])([CH3:7])[CH3:8])([CH3:9])[CH3:10].[K+:1]>>[Br:11][c:12]1[cH:13][c:14]([CH3:35])[c:15]([CH:18]2[CH2:19][CH2:20][N:27]([C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[CH2:26]2)[cH:16][cH:17]1

Participants

5

Reactant 4

HCID 813Potassium CationHCID 8028TetrahydrofuranHCID 3280088Npc316347HCID 86621498Methanesulfonic acid 3-(4-bromo-2-methyl-phenyl)-4-tert-butoxycarbonylamino-butyl ester

Product 1

HCID 66877329Tert-butyl 3-(4-bromo-2-methylphenyl)pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-0e6acab14c894265b6e687409d0ee251
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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