Acetonitrile → 7-(bromomethyl)-5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-3,4-dihydroquinazolin-2(1H)-one
Reaction equation
[C:48]([Br:49])([Br:50])([Br:51])[Br:52].[CH3:53][C:54]#[N:55].[Cl:1][c:2]1[c:3](-[c:8]2[c:9]3[c:14]([cH:15][c:16]([CH2:18][OH:19])[cH:17]2)[N:13]([c:20]2[c:21]([Cl:27])[cH:22][cH:23][cH:24][c:25]2[Cl:26])[C:12](=[O:28])[NH:11][CH2:10]3)[cH:4][cH:5][cH:6][cH:7]1.[c:29]1([P:30]([c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[cH:43][cH:44][cH:45][cH:46][cH:47]1>>[Cl:1][c:2]1[c:3](-[c:8]2[c:9]3[c:14]([cH:15][c:16]([CH2:18][Br:49])[cH:17]2)[N:13]([c:20]2[c:21]([Cl:27])[cH:22][cH:23][cH:24][c:25]2[Cl:26])[C:12](=[O:28])[NH:11][CH2:10]3)[cH:4][cH:5][cH:6][cH:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-0bb060d823144c3e816c0321a5a4c3ff
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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