反应详情

A 2.6 g. portion of hexahydro-2H-1,3-diazepin-2-thione is dissolved in 150 ml. of acetone and clarified. A 5.5 g. portion of 2-bromo-2-phenylacetophenone is added and the solution is refluxed for one hour and then stirred at room temperature for 16 hours. The solid is collected, washed with acetone and dried in vacuo at 60° C., giving 6.5 g. of the desired product, m.p. 195°-197° C. (dec.).

1. temperaturethe solution is refluxed for one hour
2. customThe solid is collected
3. washwashed with acetone
4. customdried in vacuo at 60° C.
5. customgiving 6.5 g