Dimethyl Sulfoxide → 4-(6-Fluoro-7-morpholin-4-yl-quinazolin-4-yl)-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[n:15][cH:16][n:17][c:18]3[cH:19][c:20]([F:25])[c:21]([F:24])[cH:22][c:23]23)[CH2:12][CH2:13]1.[CH2:26]1[CH2:27][O:28][CH2:29][CH2:30][NH:31]1.[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:37][S:38]([CH3:39])=[O:40]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[n:15][cH:16][n:17][c:18]3[cH:19][c:20]([N:31]4[CH2:26][CH2:27][O:28][CH2:29][CH2:30]4)[c:21]([F:24])[cH:22][c:23]23)[CH2:12][CH2:13]1Participants
5
Sources & evidence
- ORD record
- ord-460e525f802e4c7a868643e4b2021568
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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