Water → 3-(1-Benzylpiperidin-4-yl)-7-methoxy-1,3,4,5-tetrahydro-1,3-benzodiazepin-2-one

HRID 672549Notes

Reaction equation

HRID 672549 reaction equation
[NH2:1][c:2]1[c:3]([CH2:10][CH2:11][NH:12][CH:13]2[CH2:14][CH2:15][N:16]([CH2:19][c:20]3[cH:21][cH:22][cH:23][cH:24][cH:25]3)[CH2:17][CH2:18]2)[cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1.[O:27]=[CH:28][N:29]([CH3:30])[CH3:31].[OH2:26]>>[NH:1]1[c:2]2[c:3]([cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]2)[CH2:10][CH2:11][N:12]([CH:13]2[CH2:14][CH2:15][N:16]([CH2:19][c:20]3[cH:21][cH:22][cH:23][cH:24][cH:25]3)[CH2:17][CH2:18]2)[C:28]1=[O:27]

Participants

4

Reactant 3

HCID 962WaterHCID 6228DimethylformamideHCID 59626805[2-(2-Amino-5-methoxyphenyl)-ethyl]-(1-benzylpiperidin-4-yl)-amine

Product 1

HCID 596268033-(1-Benzylpiperidin-4-yl)-7-methoxy-1,3,4,5-tetrahydro-1,3-benzodiazepin-2-one

Sources & evidence

ORD record
ord-823a2991c3fe4788a2abd75ed36dc540
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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