Magnesium Cation → 2-[4-(tert-Butyl)-2-(1-Boc-piperidin-4-yloxy)benzylamino]-5-chloro-N-(5-chloropyridin-2-yl)benzamide
Reaction equation
[BH3:72].[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]([O:13][CH:14]2[CH2:15][CH2:16][N:17]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:18][CH2:19]2)[c:8]([CH:9]=[O:10])[cH:11][cH:12]1.[CH3:68][N:69]([CH3:70])[CH3:71].[CH3:73][c:74]1[cH:75][cH:76][cH:77][cH:78][cH:79]1.[Cl:27][c:28]1[cH:29][cH:30][c:31]([NH:34][C:35]([c:36]2[c:37]([NH2:43])[cH:38][cH:39][c:40]([Cl:42])[cH:41]2)=[O:44])[n:32][cH:33]1.[Mg+2:62].[O-:63][S:64](=[O:65])(=[O:66])[O-:67].[c:45]1([CH3:46])[cH:47][cH:48][c:49]([S:50]([O-:51])(=[O:52])=[O:53])[cH:54][cH:55]1.[nH+:56]1[cH:57][cH:58][cH:59][cH:60][cH:61]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]([O:13][CH:14]2[CH2:15][CH2:16][N:17]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:18][CH2:19]2)[c:8]([CH2:9][NH:43][c:37]2[c:36]([C:35]([NH:34][c:31]3[cH:30][cH:29][c:28]([Cl:27])[cH:33][n:32]3)=[O:44])[cH:41][c:40]([Cl:42])[cH:39][cH:38]2)[cH:11][cH:12]1Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-9594e5b565124fdf90d8403f2765f7fd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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