Hydrochloric Acid → 2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl N-[4-[1,3-benzodioxol-5-ylsulfonyl(2-methylpropyl)amino]-3-hydroxy-1-(4-hydroxyphenyl)butan-2-yl]carbamate

HRID 672754Notes

Reaction equation

HRID 672754 reaction equation
[CH2:48]1[O:49][CH2:50][CH2:51][O:52][CH2:53]1.[Cl:54][CH2:55][Cl:56].[ClH:45].[Na+:47].[O:1]1[CH2:2][O:3][c:4]2[c:5]1[cH:6][cH:7][c:8]([S:10](=[O:11])(=[O:12])[N:13]([CH2:14][CH:15]([CH3:16])[CH3:17])[CH2:18][CH:19]1[CH:20]([CH2:37][c:38]3[cH:39][cH:40][c:41]([OH:44])[cH:42][cH:43]3)[N:21]([C:26](=[O:27])[O:28][CH:29]3[CH2:30][O:31][CH:32]4[O:33][CH2:34][CH2:35][CH:36]34)[C:22]([CH3:24])([CH3:25])[O:23]1)[cH:9]2.[OH-:46].[OH2:57]>>[O:1]1[CH2:2][O:3][c:4]2[c:5]1[cH:6][cH:7][c:8]([S:10](=[O:11])(=[O:12])[N:13]([CH2:14][CH:15]([CH3:16])[CH3:17])[CH2:18][CH:19]([CH:20]([NH:21][C:26](=[O:27])[O:28][CH:29]1[CH2:30][O:31][CH:32]3[O:33][CH2:34][CH2:35][CH:36]13)[CH2:37][c:38]1[cH:39][cH:40][c:41]([OH:44])[cH:42][cH:43]1)[OH:23])[cH:9]2

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 6344DichloromethaneHCID 312751,4-DioxaneHCID 207741912,3,3a,4,5,6a-Hexahydrofuro[2,3-b]furan-4-yl 5-[[1,3-benzodioxol-5-ylsulfonyl(2-methylpropyl)amino]methyl]-4-[(4-hydroxyphenyl)methyl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylate

Product 1

HCID 207743092,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl N-[4-[1,3-benzodioxol-5-ylsulfonyl(2-methylpropyl)amino]-3-hydroxy-1-(4-hydroxyphenyl)butan-2-yl]carbamate

Sources & evidence

ORD record
ord-068d75dc31ea43859007bd6bd3ff4f95
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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