Bromide ion → N-(3-cyclopropyl-6-fluoro-imidazo[1,2-a]pyridin-2-yl)-2,2,2-trifluoro-acetamide
Reaction equation
[Br-:1].[Br:6][c:7]1[c:8]([NH:17][C:18]([C:19]([F:20])([F:21])[F:22])=[O:23])[n:9][c:10]2[n:11]1[cH:12][c:13]([F:16])[cH:14][cH:15]2.[CH:2]1([Zn+:5])[CH2:3][CH2:4]1.[O:24]1[CH2:25][CH2:26][CH2:27][CH2:28]1.[cH:29]1[cH:30][cH:31][c:32]([P:33]([Pd:34]([P:35]([c:36]2[cH:37][cH:38][cH:39][cH:40][cH:41]2)([c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)[c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)([P:54]([c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)([c:61]2[cH:62][cH:63][cH:64][cH:65][cH:66]2)[c:67]2[cH:68][cH:69][cH:70][cH:71][cH:72]2)[P:73]([c:74]2[cH:75][cH:76][cH:77][cH:78][cH:79]2)([c:80]2[cH:81][cH:82][cH:83][cH:84][cH:85]2)[c:86]2[cH:87][cH:88][cH:89][cH:90][cH:91]2)([c:92]2[cH:93][cH:94][cH:95][cH:96][cH:97]2)[c:98]2[cH:99][cH:100][cH:101][cH:102][cH:103]2)[cH:104][cH:105]1>>[CH:2]1([c:7]2[c:8]([NH:17][C:18]([C:19]([F:20])([F:21])[F:22])=[O:23])[n:9][c:10]3[n:11]2[cH:12][c:13]([F:16])[cH:14][cH:15]3)[CH2:3][CH2:4]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-392188c1965545fdaa332946ac1d46ae
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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