p-Toluenesulfonic acid → N-(2,6-difluorophenyl)-2-(ethyloxy)-5-(3-{2-[(2-(ethyloxy)-4-{4-[4-(methylsulfonyl)-1-piperazinyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Reaction equation
[CH2:37]([CH3:38])[O:39][c:40]1[c:41]([NH2:42])[cH:43][cH:44][c:45]([N:47]2[CH2:48][CH2:49][CH:50]([N:53]3[CH2:54][CH2:55][N:56]([S:59](=[O:60])(=[O:61])[CH3:62])[CH2:57][CH2:58]3)[CH2:51][CH2:52]2)[cH:46]1.[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:17]3[cH:18][cH:19][c:20]([O:34][CH2:35][CH3:36])[c:21]([C:22](=[O:23])[NH:24][c:25]4[c:26]([F:32])[cH:27][cH:28][cH:29][c:30]4[F:31])[cH:33]3)[n:10][c:11]3[n:12]2[cH:13][cH:14][cH:15][cH:16]3)[n:7]1.[c:63]1([CH3:64])[cH:65][cH:66][c:67]([S:68]([OH:69])(=[O:70])=[O:71])[cH:72][cH:73]1>>[c:2]1([NH:42][c:41]2[c:40]([O:39][CH2:37][CH3:38])[cH:46][c:45]([N:47]3[CH2:48][CH2:49][CH:50]([N:53]4[CH2:54][CH2:55][N:56]([S:59](=[O:60])(=[O:61])[CH3:62])[CH2:57][CH2:58]4)[CH2:51][CH2:52]3)[cH:44][cH:43]2)[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:17]3[cH:18][cH:19][c:20]([O:34][CH2:35][CH3:36])[c:21]([C:22](=[O:23])[NH:24][c:25]4[c:26]([F:32])[cH:27][cH:28][cH:29][c:30]4[F:31])[cH:33]3)[n:10][c:11]3[n:12]2[cH:13][cH:14][cH:15][cH:16]3)[n:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-99b00aa46ca34f81a173116a93787a7b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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