Pyridine → N-(5-{[2-(acetylamino) [1,3]thiazolo[5,4-b]pyridin-5-yl]oxy}-4-chloro-2-fluorophenyl)-2,2,2-trifluoroacetamide
Reaction equation
[CH3:27][C:28]([Cl:29])=[O:30].[CH3:31][N:32]([CH3:33])[c:34]1[cH:35][cH:36][n:37][cH:38][cH:39]1.[NH2:1][c:2]1[s:3][c:4]2[n:5][c:6]([O:11][c:12]3[c:13]([Cl:26])[cH:14][c:15]([F:25])[c:16]([NH:18][C:19]([C:20]([F:21])([F:22])[F:23])=[O:24])[cH:17]3)[cH:7][cH:8][c:9]2[n:10]1.[cH:40]1[cH:41][cH:42][n:43][cH:44][cH:45]1>>[NH:1]([c:2]1[s:3][c:4]2[n:5][c:6]([O:11][c:12]3[c:13]([Cl:26])[cH:14][c:15]([F:25])[c:16]([NH:18][C:19]([C:20]([F:21])([F:22])[F:23])=[O:24])[cH:17]3)[cH:7][cH:8][c:9]2[n:10]1)[C:28]([CH3:27])=[O:30]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-f3826c81ee614f6388a58091749f1285
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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