Diethyl Ether → Methyl 2-(2,4-difluorophenylamino)-5-fluoro-6-methoxynicotinate
Reaction equation
[CH3:30][CH2:31][O:32][CH2:33][CH3:34].[F:1][c:2]1[c:3]([NH:9][c:10]2[c:11]([C:12](=[O:13])[O:14][CH3:15])[cH:16][c:17]([F:21])[c:18]([OH:20])[n:19]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1.[N+:22](=[N-:23])=[CH2:24].[O:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1>>[F:1][c:2]1[c:3]([NH:9][c:10]2[c:11]([C:12](=[O:13])[O:14][CH3:15])[cH:16][c:17]([F:21])[c:18]([O:20][CH3:24])[n:19]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-26c08516880f41bba8b28ac23eea8040
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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