Dimethyl Sulfoxide → Ethyl 2-(5-bromo-3-((tetrahydro-2H-pyran-4-yl)methylamino)pyrazin-2-ylamino)acetate
Reaction equation
[Br:1][c:2]1[c:3]([NH:9][CH2:10][C:11](=[O:12])[O:13][CH2:14][CH3:15])[n:4][cH:5][c:6]([Br:8])[n:7]1.[CH3:33][S:34]([CH3:35])=[O:36].[CH3:37][OH:38].[CH:24]([N:25]([CH2:26][CH3:27])[CH:28]([CH3:29])[CH3:30])([CH3:31])[CH3:32].[O:16]1[CH2:17][CH2:18][CH:19]([CH2:22][NH2:23])[CH2:20][CH2:21]1>>[c:2]1([NH:23][CH2:22][CH:19]2[CH2:18][CH2:17][O:16][CH2:21][CH2:20]2)[c:3]([NH:9][CH2:10][C:11](=[O:12])[O:13][CH2:14][CH3:15])[n:4][cH:5][c:6]([Br:8])[n:7]1Participants
6
Sources & evidence
- ORD record
- ord-1680e346d8f340dd874a78cf092671de
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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