Tetrahydrofuran → 5-Amino-2-(2-dimethylamino-ethyl)-2H-isoquinolin-1-one

HRID 674368Notes

Reaction equation

HRID 674368 reaction equation
[CH2:23]1[O:24][CH2:25][CH2:26][CH2:27]1.[CH3:1][N:2]([CH2:3][CH2:4][n:5]1[c:6](=[O:18])[c:7]2[cH:8][cH:9][cH:10][c:11]([N+:15]([O-:16])=[O:17])[c:12]2[cH:13][cH:14]1)[CH3:19].[Sn:20]([Cl:21])[Cl:22]>>[CH3:1][N:2]([CH2:3][CH2:4][n:5]1[c:6](=[O:18])[c:7]2[cH:8][cH:9][cH:10][c:11]([NH2:15])[c:12]2[cH:13][cH:14]1)[CH3:19]

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 24479Stannous ChlorideHCID 595792672-(2-Dimethylamino-ethyl)-5-nitro-2H-isoquinolin-1-one

Product 1

HCID 595794535-Amino-2-(2-dimethylamino-ethyl)-2H-isoquinolin-1-one

Sources & evidence

ORD record
ord-8b85d11f781f4a228fa576ff47f77328
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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