2-Aminothiazole → 2-(7-chloro-3-oxo-1H-isoindol-2-yl)-3-cyclohexyl-N-(1,3-thiazol-2-yl)propanamide
Reaction equation
[CH:1]1([CH2:7][CH:8]([C:9](=[O:10])[OH:11])[N:12]2[C:13](=[O:22])[c:14]3[cH:15][cH:16][cH:17][c:18]([Cl:21])[c:19]3[CH2:20]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[CH:29]1([CH2:30][CH:31]([N:32]2[CH2:33][c:34]3[c:35]([cH:36][cH:37][cH:38][cH:39]3)[C:40]2=[O:41])[C:42]([NH:43][c:44]2[s:45][cH:46][cH:47][n:48]2)=[O:49])[CH2:50][CH2:51][CH2:52][CH2:53][CH2:54]1.[NH2:23][c:24]1[s:25][cH:26][cH:27][n:28]1>>[CH:1]1([CH2:7][CH:8]([C:9](=[O:11])[NH:23][c:24]2[s:25][cH:26][cH:27][n:28]2)[N:12]2[C:13](=[O:22])[c:14]3[cH:15][cH:16][cH:17][c:18]([Cl:21])[c:19]3[CH2:20]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Participants
4
Sources & evidence
- ORD record
- ord-ab5a2514d2c34518a750179cf7616ef0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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