Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 674884Generated: October 30, 2026

Sodium ion → 5-(4-Methyl-piperazin-1-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/674884

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium ionHCID 923—
ReactantTolueneHCID 1140—
ReactantPalladiumHCID 23938—
Reactant1-MethylpiperazineHCID 53167—
ReactantDibenzylidene acetoneHCID 95417—
Reactant2-(Di-tert-butylphosphino)biphenylHCID 2734215—
Reactant2-Methylpropan-2-olateHCID 4574913—
ReactantN-Boc-5-bromoisoindolineHCID 16102683—
Product5-(4-Methyl-piperazin-1-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl esterHCID 59263131—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-35332a5110754d3183597f9b05c29150
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)