Sodium ion → 5-(4-Methyl-piperazin-1-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester
Reaction equation
[C:18]([P:19]([C:20]([CH3:21])([CH3:22])[CH3:23])[c:24]1[cH:25][cH:26][cH:27][cH:28][c:29]1-[c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1)([CH3:36])([CH3:37])[CH3:38].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([Br:17])[cH:14][c:15]2[CH2:16]1.[CH3:108][c:109]1[cH:110][cH:111][cH:112][cH:113][cH:114]1.[CH3:39][C:40]([CH3:41])([O-:42])[CH3:43].[CH3:45][N:46]1[CH2:47][CH2:48][NH:49][CH2:50][CH2:51]1.[Na+:44].[O:54]=[C:55]([CH:56]=[CH:57][c:58]1[cH:59][cH:60][cH:61][cH:62][cH:63]1)[CH:64]=[CH:65][c:66]1[cH:67][cH:68][cH:69][cH:70][cH:71]1.[O:72]=[C:73]([CH:74]=[CH:75][c:76]1[cH:77][cH:78][cH:79][cH:80][cH:81]1)[CH:82]=[CH:83][c:84]1[cH:85][cH:86][cH:87][cH:88][cH:89]1.[O:90]=[C:91]([CH:92]=[CH:93][c:94]1[cH:95][cH:96][cH:97][cH:98][cH:99]1)[CH:100]=[CH:101][c:102]1[cH:103][cH:104][cH:105][cH:106][cH:107]1.[Pd:52].[Pd:53]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([N:49]3[CH2:48][CH2:47][N:46]([CH3:45])[CH2:51][CH2:50]3)[cH:14][c:15]2[CH2:16]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-35332a5110754d3183597f9b05c29150
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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