Hydrochloric Acid → 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-fluoro-6-(2-morpholin-4-ylethoxy)-3-quinolinecarbonitrile
Reaction equation
[Cl:1][c:2]1[c:3]([C:22]#[N:23])[cH:4][n:5][c:6]2[cH:7][c:8]([F:21])[c:9]([O:12][CH2:13][CH2:14][N:15]3[CH2:16][CH2:17][O:18][CH2:19][CH2:20]3)[cH:10][c:11]12.[Cl:24][c:25]1[c:26]([NH2:27])[cH:28][c:29]([O:33][CH3:34])[c:30]([Cl:32])[cH:31]1.[ClH:35].[n:36]1[cH:37][cH:38][cH:39][cH:40][cH:41]1>>[c:2]1([NH:27][c:26]2[c:25]([Cl:24])[cH:31][c:30]([Cl:32])[c:29]([O:33][CH3:34])[cH:28]2)[c:3]([C:22]#[N:23])[cH:4][n:5][c:6]2[cH:7][c:8]([F:21])[c:9]([O:12][CH2:13][CH2:14][N:15]3[CH2:16][CH2:17][O:18][CH2:19][CH2:20]3)[cH:10][c:11]12Participants
5
Sources & evidence
- ORD record
- ord-518d0a7e83954b3ab8f266aa123d5d4e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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