Trifluoroacetic acid → 1-Cyclopropyl-6-fluoro-3-hydroxy-7-(pyrrolidin-1-yl)-1H-quinazoline-2,4-dione
Reaction equation
[B+3:51].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][n:9]1[c:10](=[O:29])[n:11]([CH:26]2[CH2:27][CH2:28]2)[c:12]2[cH:13][c:14]([N:21]3[CH2:22][CH2:23][CH2:24][CH2:25]3)[c:15]([F:20])[cH:16][c:17]2[c:18]1=[O:19].[F:30][C:31]([F:32])([F:33])[C:34]([O-:35])=[O:36].[F:37][C:38]([F:39])([F:40])[C:41]([O-:42])=[O:43].[F:44][C:45]([F:46])([F:47])[C:48]([O-:49])=[O:50].[OH:52][C:53]([C:54]([F:55])([F:56])[F:57])=[O:58]>>[OH:8][n:9]1[c:10](=[O:29])[n:11]([CH:26]2[CH2:27][CH2:28]2)[c:12]2[cH:13][c:14]([N:21]3[CH2:22][CH2:23][CH2:24][CH2:25]3)[c:15]([F:20])[cH:16][c:17]2[c:18]1=[O:19]Participants
5
Sources & evidence
- ORD record
- ord-b34e8501946b47488488a61f0cef13fa
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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