Diisopropylamine → Ethyl 2-benzyl-2-methyl-5-trimethylsilylpent-4-ynoate
Reaction equation
[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH3:27][Si:28]([CH3:29])([CH3:30])[CH:31]([C:32]#[CH:33])[Br:34].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[O:35]1[CH2:36][CH2:37][CH2:38][CH2:39]1.[c:13]1([CH2:19][CH:20]([C:21](=[O:22])[O:23][CH2:24][CH3:25])[CH3:26])[cH:14][cH:15][cH:16][cH:17][cH:18]1>>[c:13]1([CH2:19][C:20]([C:21](=[O:22])[O:23][CH2:24][CH3:25])([CH3:26])[CH2:33][C:32]#[C:31][Si:28]([CH3:27])([CH3:29])[CH3:30])[cH:14][cH:15][cH:16][cH:17][cH:18]1Participants
6
Sources & evidence
- ORD record
- ord-de58344d5acd400186336859f14b5451
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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