Dichloromethane → N,N-Dimethyl-5-chloro-3-cyclohexyl-3-hydroxy-1-tosylindoline-2-carboxamide

HRID 675651Notes

Reaction equation

HRID 675651 reaction equation
[CH2:33]1[CH2:34][CH2:35][C:36]2=[N:41][CH2:40][CH2:39][CH2:38][N:37]2[CH2:42][CH2:43]1.[CH:1]1([C:7](=[O:8])[c:9]2[c:10]([N:16]([CH2:17][C:18]([N:19]([CH3:20])[CH3:21])=[O:22])[S:23](=[O:24])(=[O:25])[c:26]3[cH:27][cH:28][c:29]([CH3:30])[cH:31][cH:32]3)[cH:11][cH:12][c:13]([Cl:15])[cH:14]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[Cl:44][CH2:45][Cl:46]>>[CH:1]1([C:7]2([OH:8])[c:9]3[c:10]([cH:11][cH:12][c:13]([Cl:15])[cH:14]3)[N:16]([S:23](=[O:24])(=[O:25])[c:26]3[cH:27][cH:28][c:29]([CH3:30])[cH:31][cH:32]3)[CH:17]2[C:18]([N:19]([CH3:20])[CH3:21])=[O:22])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 543616542-[N-(Tosyl)-N-(dimethylcarbamoylmethyl)amino]-5-chlorophenyl cyclohexyl ketone

Product 1

HCID 23368623N,N-Dimethyl-5-chloro-3-cyclohexyl-3-hydroxy-1-tosylindoline-2-carboxamide

Sources & evidence

ORD record
ord-863c10a0f62d4b919b8123681150753a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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