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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 675653Generated: October 26, 2026

Dimethylformamide → 4-Chloro-2-(2-hydroxy-1-hydroxymethyl-ethylamino)-8-(2,6-difluoro-phenyl)-8H-pyrido[2,3-d]pyrimidin-7-one

https://huagongshe.com/reaction/675653

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
ReactantSerinolHCID 68294—
Reactant4-chloro-8-(2,6-difluorophenyl)-2-(methylsulfinyl)pyrido[2,3-d]pyrimidin-7(8H)-oneHCID 11951514—
Product4-Chloro-2-(2-hydroxy-1-hydroxymethyl-ethylamino)-8-(2,6-difluoro-phenyl)-8H-pyrido[2,3-d]pyrimidin-7-oneHCID 11951517—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-54c659d33542413aa5defcf56945dbfb
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)