Dichloromethane → 3-(5-Bromo-2-fluorobenzyloxy)-1-(piperidin-2-yl)propane
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([F:26])[c:6]([CH2:7][O:8][CH2:9][CH2:10][CH2:11][CH:12]2[N:13]([C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH2:14][CH2:15][CH2:16][CH2:17]2)[cH:25]1.[CH2:34]([Cl:35])[Cl:36].[OH:27][C:28]([C:29]([F:30])([F:31])[F:32])=[O:33]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([F:26])[c:6]([CH2:7][O:8][CH2:9][CH2:10][CH2:11][CH:12]2[NH:13][CH2:14][CH2:15][CH2:16][CH2:17]2)[cH:25]1Participants
4
Sources & evidence
- ORD record
- ord-5dc6bcfaf724438e8fc731f6b8acd8b4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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