Dichloromethane → 5-Bromo-2-(2-chlorophenylamino)-3,4-difluorobenzoic acid
Reaction equation
[Br:14][c:15]1[c:16]([F:26])[c:17]([F:25])[c:18]([F:24])[c:19]([C:20](=[O:21])[OH:22])[cH:23]1.[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH3:1][CH2:2][CH2:3][CH2:4][Li:5].[Cl:27][CH2:28][Cl:29].[Cl:6][c:7]1[c:8]([NH2:9])[cH:10][cH:11][cH:12][cH:13]1>>[Cl:6][c:7]1[c:8]([NH:9][c:18]2[c:17]([F:25])[c:16]([F:26])[c:15]([Br:14])[cH:23][c:19]2[C:20](=[O:21])[OH:22])[cH:10][cH:11][cH:12][cH:13]1Participants
6
Sources & evidence
- ORD record
- ord-dcc690bf6ced4d30bbfc575407bd5165
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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