Dichloromethane → 4-[(3,4-Dichlorophenyl)carbonyl]piperidine

HRID 676415Notes

Reaction equation

HRID 676415 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([C:14]([c:15]2[cH:16][c:17]([Cl:22])[c:18]([Cl:21])[cH:19][cH:20]2)=[O:23])[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[CH2:31]([Cl:32])[Cl:33].[OH:24][C:25]([C:26]([F:27])([F:28])[F:29])=[O:30]>>[NH:8]1[CH2:9][CH2:10][CH:11]([C:14]([c:15]2[cH:16][c:17]([Cl:22])[c:18]([Cl:21])[cH:19][cH:20]2)=[O:23])[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 53945757Tert-butyl 4-(3,4-dichlorobenzoyl)piperidine-1-carboxylate

Product 1

HCID 124044204-[(3,4-Dichlorophenyl)carbonyl]piperidine

Sources & evidence

ORD record
ord-2e22c92e7a7349528d1b37ede4b4686c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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