Ethyl Acetoacetate → HCID 20527065, compound

HRID 67659Notes

Reaction equation

HRID 67659 reaction equation
[CH2:1]([NH:13][CH2:14][CH2:15][NH2:16])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[C:17](OCC)(=[O:22])[CH2:18][C:19]([CH3:21])=O>>[CH2:1]([N:13]1[C:17](=[O:22])[CH2:18][C:19]([CH3:21])=[N:16][CH2:15][CH2:14]1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

Participants

3

Reactant 2

HCID 8868Ethyl AcetoacetateHCID 10561362N-dodecylethylenediamine

Product 1

HCID 20527065HCID 20527065, compound

Procedure

Into a four-necked flask provided with a stirrer, thermometer, gas inlet tube, and water measuring tube connected with a reflux condenser, were charged 228.1 g (1 mole) of N-dodecylethylenediamine and 130.1 g (1 mole) of ethyl acetoacetate. While bubbling nitrogen gas, the flask was heated at 150° to 160° C. to distill off 18 g of water and 46 g of ethanol, and then 4-dodecyl-7-methyl-3,6-dihydro-2H-1,4-diazepin-5-one in slight yellow liquid was obtained.

Workup

  1. customInto a four-necked flask provided with a stirrer
  2. customthermometer, gas inlet tube, and water measuring tube connected with a reflux condenser
  3. customWhile bubbling nitrogen gas
  4. temperaturethe flask was heated at 150° to 160° C.
  5. distillationto distill off 18 g of water and 46 g of ethanol

Sources & evidence

ORD record
ord-4931a80568b4470bbd0cf7091fb3cb7c
Source dataset
uspto-grants-1982_08
Patent number
US04346087

Reaction notes

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