反应详情

Into a four-necked flask provided with a stirrer, thermometer, gas inlet tube, and water measuring tube connected with a reflux condenser, were charged 228.1 g (1 mole) of N-dodecylethylenediamine and 130.1 g (1 mole) of ethyl acetoacetate. While bubbling nitrogen gas, the flask was heated at 150° to 160° C. to distill off 18 g of water and 46 g of ethanol, and then 4-dodecyl-7-methyl-3,6-dihydro-2H-1,4-diazepin-5-one in slight yellow liquid was obtained.

1. customInto a four-necked flask provided with a stirrer
2. customthermometer, gas inlet tube, and water measuring tube connected with a reflux condenser
3. customWhile bubbling nitrogen gas
4. temperaturethe flask was heated at 150° to 160° C.
5. distillationto distill off 18 g of water and 46 g of ethanol