Methyl acetoacetate → HCID 54347639, compound

HRID 67665Notes

Reaction equation

[CH2:1]([O:9][CH2:10][CH2:11][CH2:12][NH:13][CH2:14][CH2:15][NH2:16])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[C:17](OC)(=[O:22])[CH2:18][C:19]([CH3:21])=O>>[CH2:1]([O:9][CH2:10][CH2:11][CH2:12][N:13]1[C:17](=[O:22])[CH2:18][C:19]([CH3:21])=[N:16][CH2:15][CH2:14]1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

Reactant 2

HCID 7757Methyl acetoacetate

HCID 57223339N-octoxypropylethylenediamine

Product 1

HCID 54347639HCID 54347639, compound

Procedure

Into an apparatus similar to that in Example 1, were charged 230.1 g (1 mole) of N-octoxypropylethylenediamine and 116.1 g (1 mole) of methyl acetoacetate. At 140° to 145° C., 18 g of water and 32 g of ethanol were distilled off to obtain 4-octoxypropyl-7-methyl-3,6-dihydro-2H-1,4-diazepin-5-one.

Workup

distillationAt 140° to 145° C., 18 g of water and 32 g of ethanol were distilled off

Sources & evidence

ORD record: ord-b1e702d1ee1e4121a901cc5708ca2c82
Source dataset: uspto-grants-1982_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04346087

Reaction notes

Loading…