Methyl iodide → 5-Chloro-3-hydroxy-3-methyl-6-(piperidin-1-yl)-2,3-dihydrobenzofuran
Reaction equation
[CH3:19][I:20].[Cl:1][c:2]1[c:3]([N:12]2[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]2)[cH:4][c:5]2[c:6]([cH:11]1)[C:7](=[O:10])[CH2:8][O:9]2.[Mg:18]>>[Cl:1][c:2]1[c:3]([N:12]2[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]2)[cH:4][c:5]2[c:6]([cH:11]1)[C:7]([OH:10])([CH3:19])[CH2:8][O:9]2Participants
4
Sources & evidence
- ORD record
- ord-ddf45e0e70fb41b7a586988d68ce33a6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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