Tetrahydrofuran → 5-tert-Butoxycarbonylaminomethyl-2-(1-hydroxy-3,3-dimethyl-butyl)-pyridine
Reaction equation
[Br:6][c:7]1[n:8][cH:9][c:10]([CH2:13][NH:14][C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[cH:11][cH:12]1.[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[CH3:22][C:23]([CH2:24][CH:25]=[O:26])([CH3:27])[CH3:28].[Li:1][CH2:2][CH2:3][CH2:4][CH3:5]>>[c:7]1([CH:25]([CH2:24][C:23]([CH3:22])([CH3:27])[CH3:28])[OH:26])[n:8][cH:9][c:10]([CH2:13][NH:14][C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[cH:11][cH:12]1Participants
5
Sources & evidence
- ORD record
- ord-720fe01a85b845a0a90e19c10b31f076
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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