Dichloromethane → Tert-butyl 2-[1-hydroxy-2-methyl-3-(4-methyl-2-oxo-5-phenyl-1,3-oxazolidin-3-yl)-3-oxopropyl]pyrrolidine-1-carboxylate

HRID 676946Notes

Reaction equation

HRID 676946 reaction equation
[C:42]([CH3:43])([CH3:44])([CH3:45])[O:46][C:47](=[O:48])[N:49]1[CH:50]([CH:51]=[O:52])[CH2:53][CH2:54][CH2:55]1.[CH2:33]([B+:34][CH2:35][CH2:36][CH2:37][CH3:38])[CH2:39][CH2:40][CH3:41].[CH3:18][CH2:19][N:20]([CH2:21][CH3:22])[CH2:23][CH3:24].[CH3:1][CH:2]1[N:3]([C:14]([CH2:15][CH3:16])=[O:17])[C:4](=[O:13])[O:5][CH:6]1[c:7]1[cH:8][cH:9][cH:10][cH:11][cH:12]1.[Cl:56][CH2:57][Cl:58].[S:25]([O-:26])([C:27]([F:28])([F:29])[F:30])(=[O:31])=[O:32]>>[CH3:1][CH:2]1[N:3]([C:14]([CH:15]([CH3:16])[CH:51]([CH:50]2[N:49]([C:47]([O:46][C:42]([CH3:43])([CH3:44])[CH3:45])=[O:48])[CH2:55][CH2:54][CH2:53]2)[OH:52])=[O:17])[C:4](=[O:13])[O:5][CH:6]1[c:7]1[cH:8][cH:9][cH:10][cH:11][cH:12]1

Participants

7

Reactant 6

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 2758875TrifluoromethanesulfonateHCID 41507454-Methyl-5-phenyl-3-propanoyl-oxazolidin-2-oneHCID 42278151-Boc-2-FormylpyrrolidineHCID 178440531HCID 178440531, compound

Product 1

HCID 85314624Tert-butyl 2-[1-hydroxy-2-methyl-3-(4-methyl-2-oxo-5-phenyl-1,3-oxazolidin-3-yl)-3-oxopropyl]pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-dc22b8b90305446e80ebcf30573e046d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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