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13.9 g (0.1 mole) of S-methyl-isothiourea are dissolved in 50 ml of water, cooled to a temperature of 0° to 5° C., and at this temperature and with constant stirring 15 ml (0.1 mole) of chloroformic acid benzyl ester and 50 ml of 4 N sodium hydroxide are added in about 20 minutes. The precipitate formed is filtered, washed three times with 50 ml of cold water, then three times with 50 ml of n-hexane, and finally dried over phosphorpentoxide in vacuo. Yield 15.7 g (70 percent) of the named compound. M.p.: 74° to 75° C.; RF1 0.70 to 0.75.

1. temperaturecooled to a temperature of 0° to 5° C.
2. additionare added in about 20 minutes
3. customThe precipitate formed
4. filtrationis filtered
5. washwashed three times with 50 ml of cold water
6. dry with materialthree times with 50 ml of n-hexane, and finally dried over phosphorpentoxide in vacuo