Benzyl Chloride → HCID 7196680, compound

HRID 67725Notes

Reaction equation

HRID 67725 reaction equation
[NH2:1][N:2]1[C:7](=[O:8])[C:6]([CH3:9])=[N:5][NH:4][C:3]1=[S:10].C[O-].[Na+].[CH2:14](Cl)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>CO>[NH2:1][N:2]1[C:7](=[O:8])[C:6]([CH3:9])=[N:5][N:4]=[C:3]1[S:10][CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

5

Reactant 3

HCID 7503Benzyl ChlorideHCID 12842344-Amino-6-methyl-3-sulfanyl-4,5-dihydro-1,2,4-triazin-5-oneHCID 10942334Sodium Methoxide

Product 1

HCID 7196680HCID 7196680, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

6.5 Parts by weight of 4-amino-2,3-dihydro-6-methyl-3-thiono-as-triazin-5(4H)-one is added to a solution of 2.3 parts by weight of sodium methoxide in 50 parts by volume of methanol. After a few minutes 5.2 parts by weight of benzylchloride is added and the resulting mixture is stirred over night at room temperature. The solvent is removed under vacuum and the residue is washed with water to give 4.5 parts of 4-amino-3-benzylthio-6-methyl-as-triazin-5(4H)-one.

Workup

  1. customThe solvent is removed under vacuum
  2. washthe residue is washed with water

Sources & evidence

ORD record
ord-b92e151b05bc447282cdf60f817cd47a
Source dataset
uspto-grants-1982_08
Patent number
US04346220

Reaction notes

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