Ethanol → (3RS,4RS)-1-benzyl-4-(4-fluoro-phenyl)-piperidin-3-ol
Reaction equation
[Br:21][CH2:22][c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1.[CH3:29][CH2:30][OH:31].[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH:9]([OH:14])[CH2:10][NH:11][CH2:12][CH2:13]2)[cH:6][cH:7]1.[Na+:15].[Na+:16].[O-:17][C:18](=[O:19])[O-:20]>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH:9]([OH:14])[CH2:10][N:11]([CH2:22][c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[CH2:12][CH2:13]2)[cH:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-64b88cb011ad4a468ea0164d3c902fad
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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