Hydrochloric Acid → 4-(4-Chloro-3-dimethylsulfamoylphenyl)-3-methyl-2-phenylimino-4-thiazoline hydrochloride

HRID 67747Notes

Reaction equation

HRID 67747 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:9]([CH3:20])[C:10](=[N:13][C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[S:11][CH:12]=2)=[CH:4][C:3]=1[S:21](=[O:26])(=[O:25])[N:22]([CH3:24])[CH3:23].Cl>CO>[ClH:1].[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:9]([CH3:20])[C:10](=[N:13][C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=3)[S:11][CH:12]=2)=[CH:4][C:3]=1[S:21](=[O:26])(=[O:25])[N:22]([CH3:23])[CH3:24]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 3047726Metibride

Product 1

HCID 205274574-(4-Chloro-3-dimethylsulfamoylphenyl)-3-methyl-2-phenylimino-4-thiazoline hydrochloride

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

8.9 g (0.02 mole) of 4-(4-chloro-3-dimethylsulfamoylphenyl)-3-methyl-2-phenylimino-4-thiazoline in 150 ml of methanol are acidified with a saturated ethereal solution of hydrogen chloride, the solvent is distilled off and the residue is recrystallized from ethanol. Melting point 229°-233° C. (with decomposition).

Workup

  1. distillationthe solvent is distilled off
  2. customthe residue is recrystallized from ethanol

Sources & evidence

ORD record
ord-13d8be11395641aeafeeeb754b38d3b3
Source dataset
uspto-grants-1982_08
Patent number
US04346088

Reaction notes

Loading…