Acetic Acid → 1-Benzyl-4-((4-chlorophenyl)amino)piperidine-4-carbonitrile
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11](=[O:14])[CH2:12][CH2:13]1.[CH3:23][Si:24]([CH3:25])([CH3:26])[C:27]#[N:28].[CH3:31][C:32](=[O:33])[OH:34].[Cl:15][c:16]1[cH:17][cH:18][c:19]([NH2:22])[cH:20][cH:21]1.[NH4+:29].[OH-:30].[OH2:35]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11]([NH:22][c:19]2[cH:18][cH:17][c:16]([Cl:15])[cH:21][cH:20]2)([C:27]#[N:28])[CH2:12][CH2:13]1Participants
8
Sources & evidence
- ORD record
- ord-c6f90b05044d4933b3216ebf3e48f9a9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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