反应详情

2.5 g (50 mmoles) of 4-(4-chloro-3-chlorosulfonylphenyl)-3-methyl-2-phenyliminothiazolidin-4-ol hydrobromide are heated rapidly in a jacket, which has been preheated to 220° C., in vacuo (0.1 mm Hg) over phosphorus pentoxide. The substance melts with foaming, as a result of the elimination of water, and solidifies immediately after the end of the reaction, with recrystallization. Slightly green colored crystals; melting point 264° C.

1. customafter the end of the reaction
2. customwith recrystallization