Methylamine → 1-(benzo[d][1,3]dioxol-5-yl)-N-(5-((2-methoxyphenyl)(methylamino)methyl)pyridin-2-yl)cyclopropanecarboxamide

HRID 677852Notes

Reaction equation

HRID 677852 reaction equation
[CH3:1][S:2]([O:3][CH:4]([c:5]1[cH:6][n:7][c:8]([NH:9][C:10]([C:11]2([c:12]3[cH:13][cH:14][c:15]4[c:19]([cH:20]3)[O:18][CH2:17][O:16]4)[CH2:21][CH2:22]2)=[O:23])[cH:24][cH:25]1)[c:26]1[cH:27][cH:28][cH:29][cH:30][c:31]1[O:32][CH3:33])(=[O:34])=[O:35].[CH3:36][NH2:37].[O:38]1[CH2:39][O:40][c:41]2[c:42]1[cH:43][cH:44][c:45]([C:47]1([C:50](=[O:51])[NH:52][c:53]3[n:54][cH:55][c:56]([CH:59]([c:60]4[c:61]([O:66][CH3:67])[cH:62][cH:63][cH:64][cH:65]4)[N:68]([CH3:69])[CH3:70])[cH:57][cH:58]3)[CH2:48][CH2:49]1)[cH:46]2>>[O:38]1[CH2:39][O:40][c:41]2[c:42]1[cH:43][cH:44][c:45]([C:47]1([C:50](=[O:51])[NH:52][c:53]3[n:54][cH:55][c:56]([CH:59]([c:60]4[c:61]([O:66][CH3:67])[cH:62][cH:63][cH:64][cH:65]4)[NH:68][CH3:69])[cH:57][cH:58]3)[CH2:48][CH2:49]1)[cH:46]2

Participants

4

Reactant 3

HCID 6329MethylamineHCID 442364971-(benzo[d][1,3]dioxol-5-yl)-N-(5-((dimethylamino)(2-methoxyphenyl)methyl)pyridin-2-yl)cyclopropanecarboxamideHCID 57895126(6-(1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)pyridin-3-yl)(2-methoxyphenyl)methyl methanesulfonate

Product 1

HCID 578951201-(benzo[d][1,3]dioxol-5-yl)-N-(5-((2-methoxyphenyl)(methylamino)methyl)pyridin-2-yl)cyclopropanecarboxamide

Sources & evidence

ORD record
ord-e1382baaa1994ceebf634b88dcd4b214
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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