反应详情

温度

50 °C

To a mixture containing 57.9 g (0.2 mol) of palmitic N-chloramide dissolved in 500 ml tertiary butanol at 40° C. was added 17.8 g (0.2 mol) sarcosine, 16 g (0.4 mol) sodium hydroxide and 100 ml of water. The resulting mixture was heated at 50° C. for 1 hour and then acidified with 10% hydrochloric acid (pH 3) without cooling and tertiary butanol is distilled off. During distillation, the N-methyl-N'-n-pentadecyl ureidoacetic acid precipitated was first converted into 1-methyl-3-n-pentadecyl hydantoin with splitting off of water. The initially oily hydantoin crystallized out from the aqueous distillation residue to yield 59 g (91% yield) 1-methyl-3-n-pentadecyl hydantoin of the formula ##STR9## having a melting point of 58°-60° C. and the following analysis:

1. temperaturewithout cooling
2. distillationtertiary butanol is distilled off
3. distillationDuring distillation
4. customthe N-methyl-N'-n-pentadecyl ureidoacetic acid precipitated
5. customThe initially oily hydantoin crystallized out from the aqueous distillation residue